If you ever watch a soap opera you see that characters can die or so you think they can die and somehow they re-emerge completely unscathed, even though what happens in the soap opera if it happened in real life, the person most likely would be dead, not coming back to life, but unfortunately, some of these actors and actresses who portrayed these fictional characters have passed in real life due to natural causes, and mental illness.
Billy Miller as Drew Cain (died in real life)
When Drew came into the storyline he was portrayed as a veteran coming home and would often get confused with Jason Morgan. The actor who played Drew died in real life, according to Wikipedia, he suffered from bipolar, which unfortunately, he took his life on September 15, 2023.
The role Drew Cain was replaced with the current actor Cameron Mathison, who portrays a congressman. Cameron Mathison is alive.
Leslie Charleson as Monica Quartermaine (died in real life)
Monica has been on General Hospital for as long as I remember watching General Hospital. She is the owner of the Quartermain mansion, which is often seem in many of the episodes that we watch today. Although the actress who portrays Monica has passed away in real life and the role as Monica Quartermain has not been recasted, the Quartermain family still refers to Monica as if she has not passed away but alive and well, but just confined to a bed.
Monica was the chief of staff at General Hospital, but the chief of staff has been given to numerous people, especially one infamous person Dr. Liesel Obert, but the chief of staff is currently Brook Kerr as Portia Robinson.
in spite of the characters referring to Monica as if she is not dead, the fictional character may still be alive unfortunately the actress who portrayed Monica passed away due to natural causes on January 12, 2025.
Tyler Christopher as Nikolas Cassadine
Nicholas Cassadine called home to Spoon Island and has the catacombs which is basically underground tunnels that run throughout the island. He has a son named Spencer Cassadine.